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Pharmaceutical Temperature Control Units

for pharmaceutical factory

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LNEYA Pharmaceutical temperture control unit characteristics

LNEYA is your trusted partner in industries such as pharmaceuticals, chemicals, aerospace, semiconductors, and new energy. We can develop a temperature control system perfectly tailored to your specific needs.

Each of our temperature controllers is equipped with powerful temperature control performance, an easy-to-use operating system, and reliable safety protection features, ensuring excellent functionality and a worry-free experience. Through the use of feedforward PID, fuzzy self-built tree algorithms, and the LNEYA PLC controller, we provide intuitive operation that enhances the user experience.

At LNEYA, we understand that every application is unique. Therefore, we offer flexible customization of temperature control devices based on your specific requirements. You can choose from our standard models to further enhance your system’s functionality, or collaborate with our team to design a fully customized temperature control solution for your special application.

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No matter whether you are in pharmaceutical production, research laboratories, manufacturing environments, or temperature-controlled storage and transportation, ensuring precise temperature control is crucial. LNEYA’s advanced pharmaceutical temperature control units can help you achieve optimal temperature management, ensuring stability and efficiency in production, R&D, and transportation.

TCS series

-120°C

lowest

250°C

Highest

±1°C

Temperature control accuracy


Control mode Feed forward PiD + Our special dynamic control calculation, LNEYA PLC controller
Communication protocol MODBUS RTU protocol, RS485 interface, optional Ethemet interface/R232 interface
Temp control selection Process temp control
Temp feedback The temp of three points: the inlet and outet of heat-conducing medium, material in reactor(External temp), PT100 sensor
Process temp feedback Raw material process feedback:PT100 or 4-20mA or communication given
Temp accuracy ±1℃
Input and display 7-inch color touch screen, temperature graph display
Safety protection Self-diagnosis funcion;freezer overoad protecion; high pressure switch;, overload relay; themal protection device; high temp Protection and temp faut protecion
Perform valve piece Proportional control valve control signal 4-20mA
Case material SUS304
Shell materia Cold rolled sheet (REL7035)

Principle of o Pharmaceutical temperature control Unit

  • The method of changing the control set value can respond to the system lag in the process as quickly as possible and obtain a smaller system overshoot. The control consists of two sets of PID control loops, which are called: main loop and slave loop. The control output of the main loop is used as the set value of the slave loop. By controlling the temperature change gradient in this way, the temperature control accuracy of the system is guaranteed.
  • The specially designed hysteresis predictor generates a dynamic signal yc(t) instead of the process variable y(t) as a feedback signal. Generate an e(t) signal for the controller, so that the controller predicts that the control action has no large lag.
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(Control the temperature of the reactor material)

1.Direct TCU
Direct heating/cooling: the medium flows directly through the reaction vessel without secondary heat exchange.
Simple structure: fewer system components, relatively easy installation and maintenance.
Fast response speed: quickly adjust the temperature, suitable for processes that require rapid temperature changes.

2.Secondary heat exchanger type TCU
Indirect heating/cooling: the temperature of the reaction vessel is indirectly controlled by a heat exchanger, and the medium does not directly contact the reactants.
Complex structure: The system includes additional heat exchangers, making installation and maintenance more complicated.
Precise temperature control: Suitable for processes with extremely high requirements for temperature control.

LNEYA never disappoints users！

Application of TCS series


  •  Biopharmaceuticals: In the production of biopharmaceuticals such as laboratory antibodies and vaccines, TCUs provide pharmaceutical controlled room temperature  for bioreactors, ensuring the stability of cell culture and product expression.  
  •  Chemical Synthesis: In drug synthesis, TCUs control the temperature within reactors to ensure that chemical reactions occur under optimal conditions, improving product yield and purity.  
  •  Sterile Production: In the production of sterile products like injectables and infusions, TCUs provide precise temperature control, ensuring a sterile environment and preventing contamination.  
  •  Fermentation Process Temperature Control: In biopharmaceuticals, the fermentation process requires strict temperature control to ensure the optimal growth environment for microorganisms. TCUs maintain a constant temperature, improving fermentation efficiency and product quality.  
  •  Crystallization Process Temperature Control: In drug crystallization, temperature changes directly affect the morphology and size of crystals. TCUs can precisely control the temperature gradient during the crystallization process, optimizing crystal quality.  
  •  Temperature Control During Storage and Transportation: TCUs are used in refrigerated trucks, cold storage, and other settings to ensure pharmaceutical temperature controlled transport.  
  •  Sterilization Process Temperature Control: TCUs maintain the required temperature within sterilization equipment to ensure thorough sterilization.  
  •  Drying Process Control: TCUs precisely control drying temperatures to ensure product quality.  
  •  Reactor Temperature Control: In drug synthesis, precise temperature control within reactors is necessary to guarantee reaction efficiency and product quality.  
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We are a very powerful chiller supplier with our own factory and more than 20 years of experience in the field of temperature control

Representative to obtain a standard product catalog for Pharmaceutical temperture control units, or customize.

 

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Get in touch with our Pharmaceutical temperature control unit experts

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Thermal control system is a device that can quickly adjust the heating and cooling power. By controlling the heat exchanger of the system, precise control of the heating and cooling process is achieved. When heating is required, the system can quickly increase the heating power to quickly reach the required temperature of the material; when cooling is required, the system can quickly reduce the heating power and quickly discharge the heat through the heat exchanger to quickly cool the material. This ability to switch quickly makes the entire production process stable.

Yes. LNEYA will also assist you with installation and commissioning. After you complete the acceptance process, our after-sales service engineers will provide technical training until you are proficient in operation. Should you have any questions during use, you can consult us regarding technical issues, and we will provide support either online or offline depending on the situation.
 
Additionally, LNEYA promises that once you purchase our equipment, we will offer lifetime after-sales support and maintenance (with a one-year free warranty, after which maintenance fees will apply depending on the situation).

LNEYA recommends selecting a Pharmaceutical TCU from the following perspectives:

  • Process Requirements:

If rapid temperature changes and medium compatibility are required, a direct type should be chosen.

If high temperature control accuracy or medium incompatibility is needed, choose a secondary heat exchange type.

  • Medium Compatibility:

When the medium is compatible, the direct type is more convenient.

When the medium is incompatible, the secondary heat exchange type is safer.

  • Temperature Range:

For medium to low temperature or medium to high temperature processes, the direct type is suitable.

For extreme temperature processes, the secondary heat exchange type is more appropriate.

  • Cleanliness Requirements:

For processes with high cleanliness requirements, the secondary heat exchange type is more suitable.

  • Space and Maintenance:

If space is limited or maintenance simplicity is preferred, the direct type is a better option.

If complex installation and maintenance are acceptable, the secondary heat exchange type can be chosen.

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